A Review in Management of Testicular Cancer: Single Center Review

نویسندگان

  • Ammar Hameed
  • Bob White
  • Frank Chinegwundoh
  • Ali Thwaini
  • Ajay Pahuja
چکیده

Background Testicular cancer is one of the few solid cancers that can be cured even when it is metastasized with overall survival rate of more than 90%. The aim of this study was to establish the age adjusted incidence of testicular cancer and to critically assess the management of testicular tumor. Methods This is a quantitative retrospective study utilizing a review of clinical notes for patients who underwent testicular orchidectomy. The number of cancer cases, types of pathology and cancer staging were examined. Results There is no substantial difference between the crude and the age-standardized incidence, moreover no difference from the reported crude incidence by the Scottish intercollegiate guidelines. We found 55.1% of seminoma, 14.28% of non-seminoma and 30.61% of combined (seminoma and non-seminoma), and stage I disease in 61.22% of cases, stage II in 36.73% of cases, and stage IV in 2.04% of cases. Most of the cancers were in the age group 20 - 50 with the majority (48.97%) in the age group 31 - 40. About 42.85% of cases were identified with high tumor markers; higher percentage of seminoma at stage II (40.74%). Conclusions There is no substantial difference between the crude and the age-standardized incidence, moreover no difference from the reported crude incidence. Most of the cancers were in the age group 20 - 50 with the majority (48.97%) in the age group 31 - 40. Only 25% of seminomas had elevated tumor markers. Moreover, it is important to re-enforce strict adaptation to the IGCCCG prognostic factor-based classifications.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Management of Perinatal Testicular Torsion: A Single Centre Experience

Perinatal testicular torsion (PTT) is a rare entity. The management of PTT is controversial, due to the low viability of the testis and the possibility of bilateral torsion. This is a review of our experience with six cases of PTT, highlighting diagnostic and therapeutic difficulties of this condition.

متن کامل

The Incidence of Childhood Cancer in Iran: A systematic review and meta-analysis

Background: Childhood cancer (ChC) is very rare and occurs between birth and 14 years of age. There are several reports about ChC incidence from various regions of Iran, but with conflicting results.  The present study aimed to do a systematic review to estimate the accurate incidence rate of ChC among Iranian people. Materials and Methods: This systematic review was performed based on the pre...

متن کامل

A Review on Application of Three Dimensional Culture and Testicular Scaffolds to Induction of in-Vitro Spermatogenesis

Introduction: Induction of in vitro spermatogenesis can be useful for infertility treatment in azoospermic patients and those undergoing chemotherapy. Different culture systems have been used to achieve this goal. This review study was performed with the aim to evaluate the application of 3D culture and testicular scaffolds in the establishment of in vitro spermatogenesis. In this review study...

متن کامل

The Therapeutic Effect of Statins on Survival of Patients with Gastrointestinal Cancer: a Review

Cancer -can significantly have ruining effects on very high of human beings, social, and economic condition. Gastrointestinal (GI) cancer has been reported as one of the most prevalent cancers and the incidence rates of this disorder is increasing across the world. This review explains practical recommendations for the management and improvement of patients with GI cancer by statins. Statins, a...

متن کامل

Risk of Cancer in Occupational Exposure to Radar Radiation: A Systematic Review

Background and aim: Microwave radiations are one of the most environmental workplace factors that exposed too many workers. In microwave spectrum, radar frequency with 1-300 GHz range have varied applications such as satellite, communications, military, Network, navigation, air-traffic Control, navigation, marine and weather. Uncontrolled occupational exposure to radar radiation caused to vari...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2011